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Insulin helps your body regulate production and storage of glucose, while amylin helps control the rate at which glucose enters the bloodstream after meals. People with type 1 diabetes generate neither insulin nor amylin, and with insulin alternative alone, with intensive basal/bolus therapy even, managing blood sugar becomes a daily balancing action, said Matthew Riddle, M.D., Professor of Medication, Division of Endocrinology, Diabetes, & Clinical Nutrition, Oregon Wellness & Science University. Pramlintide may provide additional benefit for these individuals by stabilizing their blood sugar levels, so they spend additional time in the normal glucose range.